Staphylococcus aureus remains a versatile and dangerous pathogen in humans causing community- and hospital-acquired infections with substantial morbidity and mortality. The pathogen can lead to asymptomatic carriage, but also produce disease ranging from circumscribed skin and soft tissue infections to invasive and life threatening bloodstream infections with metastatic seeding, severe sepsis and endocarditis. Our research projects focus on host-pathogen interaction in individuals with S. aureus colonisation and patients with S. aureus infections of different severity. Clinical research interests include epidemiology, diagnostic and therapeutic management and quality of care indicators in patients with S. aureus bacteremia.